New research has revealed an unexpected new mechanism through which the killer fungus Candida auris is resisting antifungal drug treatment. A team led by the University of Exeter and City St George’s, University of London, discovered that the fungus creates multiple versions of its entire genome, including mutating a gene that plays a role in cell wall integrity, called “Crazy-one” (CRZ1).
Candida auris copies its entire genome to survive antifungal treatment, research reveals